Pseudomonas aeruginosa PAO1, PA0997 (pqsB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0997
Name
pqsB
Replicon chromosome
Genomic location 1080009 - 1080860 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs
CommentQuinolone signal response

Cross-References

RefSeq NP_249688.1
GI 15596194
Affymetrix PA0997_at
DNASU PaCD00006460
Entrez 883098
GenBank AAG04386.1
INSDC AAG04386.1
NCBI Locus Tag PA0997
protein_id(GenBank) gb|AAG04386.1|AE004532_10|gnl|PseudoCAP|PA0997
TIGR NTL03PA00998
UniParc UPI00000C51F9
UniProtKB Acc Q9I4X2
UniProtKB ID Q9I4X2_PSEAE
UniRef100 UniRef100_W0YKP3
UniRef50 UniRef50_Q02IG2
UniRef90 UniRef90_Q02IG2

Product

Feature Type CDS
Coding Frame 1
Product Name
PqsB
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -11.88
Kyte-Doolittle Hydrophobicity Value -0.050
Molecular Weight (kDa) 30.5
Isoelectric Point (pI) 4.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6ET0 TRANSFERASE 10/25/17 Crystal structure of PqsBC (C129A) mutant from Pseudomonas aeruginosa (crystal form 1) PSEUDOMONAS AERUGINOSA PAO1 1.53 X-RAY DIFFRACTION 100.0
6ET2 TRANSFERASE 10/25/17 Crystal structure of PqsBC (C129A) mutant from Pseudomonas aeruginosa (crystal form 3) PSEUDOMONAS AERUGINOSA PAO1 2.6 X-RAY DIFFRACTION 100.0
6ESZ TRANSFERASE 10/25/17 Crystal structure of PqsBC from Pseudomonas aeruginosa (crystal form 1) PSEUDOMONAS AERUGINOSA PAO1 1.84 X-RAY DIFFRACTION 100.0
6ET3 TRANSFERASE 10/25/17 Crystal structure of PqsBC (C129S) mutant from Pseudomonas aeruginosa (crystal form 4) PSEUDOMONAS AERUGINOSA PAO1 2.25 X-RAY DIFFRACTION 100.0
6ET1 TRANSFERASE 10/25/17 Crystal structure of PqsBC from Pseudomonas aeruginosa (crystal form 2) PSEUDOMONAS AERUGINOSA PAO1 2.65 X-RAY DIFFRACTION 100.0
5DWZ TRANSFERASE 09/23/15 Structural and functional characterization of PqsBC, a condensing enzyme in the biosynthesis of the Pseudomonas aeruginosa quinolone signal PSEUDOMONAS AERUGINOSA 2.04 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 13 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000960 (301 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0997
Search term: pqsB
Search term: PqsB

References

No references are associated with this feature.