Pseudomonas aeruginosa PAO1, PA1100 (fliE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1100
Name
fliE
Replicon chromosome
Genomic location 1192053 - 1192382 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1

Cross-References

RefSeq NP_249791.1
GI 15596297
Affymetrix PA1100_fliE_at
DNASU PaCD00006507
Entrez 882031
GenBank AAG04489.1
INSDC AAG04489.1
NCBI Locus Tag PA1100
protein_id(GenBank) gb|AAG04489.1|AE004540_9|gnl|PseudoCAP|PA1100
TIGR NTL03PA01101
UniParc UPI000012A99E
UniProtKB Acc Q51462
UniProtKB ID FLIE_PSEAE
UniRef100 UniRef100_B7UX89
UniRef50 UniRef50_Q884X9
UniRef90 UniRef90_A6V990

Product

Feature Type CDS
Coding Frame 1
Product Name
flagellar hook-basal body complex protein FliE
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -3.01
Kyte-Doolittle Hydrophobicity Value -0.107
Molecular Weight (kDa) 11.9
Isoelectric Point (pI) 4.48

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Flagellar
Note: This is based on PSORTb V3.0 secondary localization prediction
Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0273
Category Flagella
Evidence
Host Organism
Notes
Reference 14617143

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 236 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001061 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1100
Search term: fliE

Human Homologs

References

Characterization of the fliE genes of Escherichia coli and Salmonella typhimurium and identification of the FliE protein as a component of the flagellar hook-basal body complex.
Müller V, Jones CJ, Kawagishi I, Aizawa S, Macnab RM
J Bacteriol 1992 Apr;174(7):2298-304
PubMed ID: 1551848
Cloning and characterization of Pseudomonas aeruginosa fliF, necessary for flagellar assembly and bacterial adherence to mucin.
Arora SK, Ritchings BW, Almira EC, Lory S, Ramphal R
Infect Immun 1996 Jun;64(6):2130-6
PubMed ID: 8675317