Pseudomonas aeruginosa PAO1, PA1240

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA1240
Name
Replicon chromosome
Genomic location 1341851 - 1342648 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249931.1
GI 15596437
Affymetrix PA1240_at
Entrez 881179
GenBank AAG04629.1
INSDC AAG04629.1
NCBI Locus Tag PA1240
protein_id(GenBank) gb|AAG04629.1|AE004553_6|gnl|PseudoCAP|PA1240
TIGR NTL03PA01241
UniParc UPI00000C52C9
UniProtKB Acc Q9I498
UniProtKB ID Q9I498_PSEAE
UniRef100 UniRef100_S0HYR9
UniRef50 UniRef50_A5CQ24
UniRef90 UniRef90_S0HYR9

Product

Feature Type CDS
Coding Frame 1
Product Name
probable enoyl-CoA hydratase/isomerase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.09
Kyte-Doolittle Hydrophobicity Value -0.115
Molecular Weight (kDa) 28.6
Isoelectric Point (pI) 5.46

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3LAO lyase, isomerase 01/06/10 Crystal Structure of Enoyl-CoA Hydratase from Pseudomonas aeruginosa PA01 PSEUDOMONAS AERUGINOSA 2.4 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 440 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001192 (166 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1240

References

A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map.
Aiba H, Baba T, Hayashi K, Inada T, Isono K, Itoh T, Kasai H, Kashimoto K, Kimura S, Kitakawa M, Kitagawa M, Makino K, Miki T, Mizobuchi K, Mori H, Mori T, Motomura K, Nakade S, Nakamura Y, Nashimoto H, Nishio Y, Oshima T, Saito N, Sampei G, Horiuchi T
DNA Res. 1996 Dec;3(6):363-77
PubMed ID: 9097039