Pseudomonas aeruginosa PAO1, PA1311 (phnX)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1311
Name
phnX
Replicon chromosome
Genomic location 1421477 - 1422304 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_250002.1
GI 15596508
Affymetrix PA1311_phnX_at
DNASU PaCD00006604
Entrez 881484
GenBank AAG04700.1
INSDC AAG04700.1
NCBI Locus Tag PA1311
protein_id(GenBank) gb|AAG04700.1|AE004560_8|gnl|PseudoCAP|PA1311
TIGR NTL03PA01312
UniParc UPI00000C5306
UniProtKB Acc Q9I433
UniProtKB ID PHNX_PSEAE
UniRef100 UniRef100_Q9I433
UniRef50 UniRef50_Q9I433
UniRef90 UniRef90_Q9I433

Product

Feature Type CDS
Coding Frame 1
Product Name
2-phosphonoacetaldehyde hydrolase
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -13.15
Kyte-Doolittle Hydrophobicity Value 0.031
Molecular Weight (kDa) 29.9
Isoelectric Point (pI) 4.45

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 120 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001254 (461 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1311
Search term: phnX

Human Homologs

References

Phosphonoacetaldehyde hydrolase from Pseudomonas aeruginosa: purification properties and comparison with Bacillus cereus enzyme.
Dumora C, Lacoste AM, Cassaigne A
Biochim Biophys Acta 1989 Aug 31;997(3):193-8
PubMed ID: 2504289
Molecular cloning, mapping, and regulation of Pho regulon genes for phosphonate breakdown by the phosphonatase pathway of Salmonella typhimurium LT2.
Jiang W, Metcalf WW, Lee KS, Wanner BL
J Bacteriol 1995 Nov;177(22):6411-21
PubMed ID: 7592415
First characterization of the phosphonoacetaldehyde hydrolase gene of Pseudomonas aeruginosa.
Dumora C, Marche M, Doignon F, Aigle M, Cassaigne A, Crouzet M
Gene 1997 Sep 15;197(1-2):405-12
PubMed ID: 9332393