Pseudomonas aeruginosa PAO1, PA1313

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1313
Name
Replicon chromosome
Genomic location 1423374 - 1424732 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250004.1
GI 15596510
Affymetrix PA1313_at
Entrez 881630
GenBank AAG04702.1
INSDC AAG04702.1
NCBI Locus Tag PA1313
protein_id(GenBank) gb|AAG04702.1|AE004560_10|gnl|PseudoCAP|PA1313
TIGR NTL03PA01314
UniParc UPI00000C5308
UniProtKB Acc Q9I431
UniProtKB ID Q9I431_PSEAE
UniRef100 UniRef100_U9HQA2
UniRef50 UniRef50_D4E2K7
UniRef90 UniRef90_B7UVR3

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 20.67
Kyte-Doolittle Hydrophobicity Value 0.840
Molecular Weight (kDa) 47.2
Isoelectric Point (pI) 11.15

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 485 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001256 (359 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1313

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Sequence and transcriptional analysis of the Streptomyces glaucescens tcmAR tetracenomycin C resistance and repressor gene loci.
Guilfoile PG, Hutchinson CR
J Bacteriol 1992 Jun;174(11):3651-8
PubMed ID: 1592819
Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin.
Bibb MJ, Sherman DH, Omura S, Hopwood DA
Gene 1994 May 3;142(1):31-9
PubMed ID: 8181754
EmrR is a negative regulator of the Escherichia coli multidrug resistance pump EmrAB.
Lomovskaya O, Lewis K, Matin A
J Bacteriol 1995 May;177(9):2328-34
PubMed ID: 7730261