Pseudomonas aeruginosa UCBPP-PA14, PA14_01120 (tsi6)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_01120
Name
tsi6
Replicon chromosome
Genomic location 110675 - 110959 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs
CommentHcp Secretion Island-I-encoded type VI secretion system (H1-T6SS)

Cross-References

RefSeq YP_788249.1
GI 116053812
Entrez 4383510
INSDC ABJ15048.1
NCBI Locus Tag PA14_01120
UniParc UPI000045D388
UniProtKB Acc Q02UY7
UniProtKB ID Q02UY7_PSEAB
UniRef100 UniRef100_Q02UY7
UniRef50 UniRef50_A9BU08
UniRef90 UniRef90_Q02UY7

Product

Feature Type CDS
Coding Frame 1
Product Name
Tsi6
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) 2.44
Kyte-Doolittle Hydrophobicity Value -0.018
Molecular Weight (kDa) 10.5
Isoelectric Point (pI) 9.14

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 6 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000091 (321 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_01120
Search term: tsi6
Search term: Tsi6

References

An interbacterial NAD(P)(+) glycohydrolase toxin requires elongation factor Tu for delivery to target cells.
Whitney JC, Quentin D, Sawai S, LeRoux M, Harding BN, Ledvina HE, Tran BQ, Robinson H, Goo YA, Goodlett DR, Raunser S, Mougous JD
Cell 2015 Oct;163(3):607-19
PubMed ID: 26456113
RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A.
Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):7707-7712.
PubMed ID: 28673999