Pseudomonas aeruginosa UCBPP-PA14, PA14_04820 (laoR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_04820
Name
laoR
Replicon chromosome
Genomic location 425972 - 426619 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs
Comment

Cross-References

RefSeq YP_788539.1
GI 116054096
Entrez 4383755
INSDC ABJ15332.1
NCBI Locus Tag PA14_04820
UniParc UPI00000C502B
UniProtKB Acc Q02U47
UniProtKB ID Q02U47_PSEAB
UniRef100 UniRef100_W0YLD2
UniRef50 UniRef50_Q4K4B1
UniRef90 UniRef90_W0YLD2

Product

Feature Type CDS
Coding Frame 1
Product Name
LaoR
Product Name Confidence: Class 1
Synonyms TetR family transcriptional regulator
Evidence for Translation
Charge (pH 7) -4.38
Kyte-Doolittle Hydrophobicity Value -0.145
Molecular Weight (kDa) 24.5
Isoelectric Point (pI) 5.89

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 143 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000358 (518 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_04820
Search term: laoR
Search term: LaoR

Human Homologs

References

LaoABCR, a Novel System for Oxidation of Long-Chain Alcohols Derived from SDS and Alkane Degradation in Pseudomonas aeruginosa.
Panasia G, Philipp B
Appl Environ Microbiol 2018 Jul 1;84(13)
PubMed ID: 29678916