Pseudomonas aeruginosa UCBPP-PA14, PA14_09340 (fptA)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_09340
Name	fptA
Replicon	chromosome
Genomic location	800018 - 802180 (+ strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	11 transposon mutants in orthologs

Cross-References

RefSeq	YP_788898.1
GI	116052258
Entrez	4385695
INSDC	ABJ13494.1
NCBI Locus Tag	PA14_09340
UniParc	UPI000012ABC9
UniProtKB Acc	Q02T38
UniProtKB ID	Q02T38_PSEAB
UniRef100	UniRef100_P42512
UniRef50	UniRef50_P42512
UniRef90	UniRef90_P42512

Product

Feature Type	CDS
Coding Frame	1
Product Name	Fe(III)-pyochelin outer membrane receptor
Synonyms
Evidence for Translation
Charge (pH 7)	-4.85
Kyte-Doolittle Hydrophobicity Value	-0.554
Molecular Weight (kDa)	80.0
Isoelectric Point (pI)	6.11

Subcellular localization

Individual Mappings	Localization Confidence PMID Outer Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
1XKW	MEMBRANE PROTEIN	09/30/04	Pyochelin outer membrane receptor FptA from Pseudomonas aeruginosa	Pseudomonas aeruginosa	2	X-RAY DIFFRACTION	100.0

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name	Source Accession	Source DB	Version	Target Accession	Target Description	Percent Identity	Alignment Length	E-Value
Lauryl Dimethylamine-N-Oxide	DB04147	DrugBank	5.1.4	P42512	Fe(3+)-pyochelin receptor	100.0	720	0.0e+00

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 250 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001486 (1037 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_09340 Search term: fptA Search term: Fe(III)-pyochelin outer membrane receptor

Human Homologs

References