Pseudomonas aeruginosa UCBPP-PA14, PA14_09530 (mexH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_09530
Name
mexH
Replicon chromosome
Genomic location 819408 - 820520 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq YP_788913.1
GI 116052243
Entrez 4382216
INSDC ABJ13479.1
NCBI Locus Tag PA14_09530
UniParc UPI00003962EC
UniProtKB Acc Q02T23
UniProtKB ID Q02T23_PSEAB
UniRef100 UniRef100_Q02T23
UniRef50 UniRef50_W0YVS7
UniRef90 UniRef90_W0YVS7

Product

Feature Type CDS
Coding Frame 1
Product Name
RND efflux membrane fusion protein
Synonyms
Evidence for Translation
Charge (pH 7) 1.70
Kyte-Doolittle Hydrophobicity Value 0.015
Molecular Weight (kDa) 39.2
Isoelectric Point (pI) 8.42

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
MexH MexH is the membrane fusion protein of the efflux complex MexGHI-OpmD. [PMID:12917802, PMID:15817779] ARO:3000807 protein homolog model Strict 686.4 99.73 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 450 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001501 (811 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_09530
Search term: mexH

Human Homologs

References

No references are associated with this feature.