Pseudomonas aeruginosa UCBPP-PA14, PA14_10630 (hpcC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_10630
Name
hpcC
Replicon chromosome
Genomic location 915383 - 916843 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq YP_788999.1
GI 116052157
Entrez 4382130
INSDC ABJ13393.1
NCBI Locus Tag PA14_10630
UniParc UPI00003962A7
UniProtKB Acc Q02ST7
UniProtKB ID Q02ST7_PSEAB
UniRef100 UniRef100_Q02ST7
UniRef50 UniRef50_Q5SJP9
UniRef90 UniRef90_Q4KBA6

Product

Feature Type CDS
Coding Frame 1
Product Name
5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -4.28
Kyte-Doolittle Hydrophobicity Value -0.103
Molecular Weight (kDa) 53.0
Isoelectric Point (pI) 6.38

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 603 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001576 (596 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_10630
Search term: hpcC

Human Homologs

Ensembl 110, assembly GRCh38.p14
aldehyde dehydrogenase 8 family member A1 [Source:HGNC Symbol;Acc:HGNC:15471]
E-value: 3.2e-112
Percent Identity: 40.9

References

No references are associated with this feature.