Pseudomonas aeruginosa UCBPP-PA14, PA14_10670 (aph)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_10670
Name
aph
Replicon chromosome
Genomic location 919472 - 920275 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14

Cross-References

RefSeq YP_789003.1
GI 116052153
Entrez 4382126
INSDC ABJ13389.1
NCBI Locus Tag PA14_10670
UniParc UPI0000E448F3
UniProtKB Acc Q02ST3
UniProtKB ID Q02ST3_PSEAB
UniRef100 UniRef100_Q02ST3
UniRef50 UniRef50_B4EF73
UniRef90 UniRef90_Q9HWR2

Product

Feature Type CDS
Coding Frame 1
Product Name
aminoglycoside 3'-phosphotransferase type IIB
Synonyms
Evidence for Translation
Charge (pH 7) -12.97
Kyte-Doolittle Hydrophobicity Value -0.295
Molecular Weight (kDa) 29.8
Isoelectric Point (pI) 4.82

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
APH(3')-IIb APH(3')-IIb is a chromosomal-encoded aminoglycoside phosphotransferase in P. aeruginosa. [PMID:14638496, PMID:10984043] ARO:3002645 protein homolog model Strict 534.3 98.51 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 63 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001579 (319 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_10670
Search term: aph

Human Homologs

References

No references are associated with this feature.