Pseudomonas aeruginosa UCBPP-PA14, PA14_11130

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_11130
Name
Replicon chromosome
Genomic location 967444 - 968133 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_789041.1
GI 116052115
Entrez 4382068
INSDC ABJ13351.1
NCBI Locus Tag PA14_11130
UniParc UPI0000396283
UniProtKB Acc Q02SP5
UniProtKB ID Q02SP5_PSEAB
UniRef100 UniRef100_S0J733
UniRef50 UniRef50_Q5P560
UniRef90 UniRef90_S0J733

Product

Feature Type CDS
Coding Frame 1
Product Name
short chain dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -3.58
Kyte-Doolittle Hydrophobicity Value 0.075
Molecular Weight (kDa) 24.3
Isoelectric Point (pI) 5.07

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5WQO OXIDOREDUCTASE 11/27/16 Crystal structure of a carbonyl reductase from Pseudomonas aeruginosa PAO1 in complex with NADP (condition I) Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.78 X-RAY DIFFRACTION 99.1
5WQN OXIDOREDUCTASE 11/27/16 Crystal structure of a carbonyl reductase from Pseudomonas aeruginosa PAO1 (condition II) Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2 X-RAY DIFFRACTION 99.1
5WQM OXIDOREDUCTASE 11/27/16 Crystal structure of a carbonyl reductase from Pseudomonas aeruginosa PAO1 (condition I) Pseudomonas aeruginosa PAO1 2.6 X-RAY DIFFRACTION 99.1
5WQP OXIDOREDUCTASE 11/27/16 Crystal structure of a carbonyl reductase from Pseudomonas aeruginosa PAO1 in complex with NADP (condition II) Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.7 X-RAY DIFFRACTION 99.1

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 505 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001607 (450 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_11130

Human Homologs

References

No references are associated with this feature.