Pseudomonas aeruginosa UCBPP-PA14, PA14_11860

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_11860
Name
Replicon	chromosome
Genomic location	1027770 - 1028399 (+ strand)

Cross-References

RefSeq	YP_789100.1
GI	116052057
Entrez	4382029
INSDC	ABJ13293.1
NCBI Locus Tag	PA14_11860
UniParc	UPI0000131194
UniProtKB Acc	Q02SI6
UniProtKB ID	Q02SI6_PSEAB
UniRef100	UniRef100_Q9HX08
UniRef50	UniRef50_Q9HX08
UniRef90	UniRef90_Q9HX08

Product

Feature Type	CDS
Coding Frame	1
Product Name	aromatic acid decarboxylase
Synonyms
Evidence for Translation
Charge (pH 7)	-6.20
Kyte-Doolittle Hydrophobicity Value	0.153
Molecular Weight (kDa)	22.4
Isoelectric Point (pI)	4.81

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
6QLH	TRANSFERASE	02/01/19	Crystal structure of UbiX in complex with reduced FMN and isopentyl monophosphate	Pseudomonas aeruginosa	1.57	X-RAY DIFFRACTION	100.0
6QLI	TRANSFERASE	02/01/19	Crystal structure of F181Q UbiX in complex with FMN and dimethylallyl monophosphate	Pseudomonas aeruginosa	1.99	X-RAY DIFFRACTION	99.5
4ZAY	LYASE	04/14/15	Structure of UbiX E49Q in complex with a covalent adduct between dimethylallyl monophosphate and reduced FMN	Pseudomonas aeruginosa	1.54	X-RAY DIFFRACTION	99.5
6QLK	TRANSFERASE	02/01/19	Crystal structure of F181H UbiX in complex with prFMN	Pseudomonas aeruginosa	1.78	X-RAY DIFFRACTION	99.5
3ZQU	LYASE	06/11/11	STRUCTURE OF A PROBABLE AROMATIC ACID DECARBOXYLASE	PSEUDOMONAS AERUGINOSA	1.5	X-RAY DIFFRACTION	100.0
4ZAW	LYASE	04/14/15	Structure of UbiX in complex with reduced prenylated FMN	Pseudomonas aeruginosa	1.89	X-RAY DIFFRACTION	100.0
4ZAZ	LYASE	04/14/15	Structure of UbiX Y169F in complex with a covalent adduct formed between reduced FMN and dimethylallyl monophosphate	Pseudomonas aeruginosa	1.45	X-RAY DIFFRACTION	99.5
4ZAG	LYASE	04/13/15	Structure of UbiX E49Q mutant in complex with oxidised FMN and dimethylallyl monophosphate	Pseudomonas aeruginosa	1.68	X-RAY DIFFRACTION	99.5
6QLL	TRANSFERASE	02/01/19	Crystal structure of F181H UbiX in complex with FMN and dimethylallyl monophosphate	Pseudomonas aeruginosa	1.56	X-RAY DIFFRACTION	99.5
4ZAV	LYASE	04/14/15	UbiX in complex with a covalent adduct between dimethylallyl monophosphate and reduced FMN	Pseudomonas aeruginosa	1.4	X-RAY DIFFRACTION	100.0
6QLV	TRANSFERASE	02/01/19	Crystal structure of W200H UbiX in complex with a geranyl-FMN N5 adduct	Pseudomonas aeruginosa	2.391	X-RAY DIFFRACTION	99.5
4ZAL	LYASE	04/13/15	Structure of UbiX E49Q mutant in complex with reduced FMN and dimethylallyl monophosphate	Pseudomonas aeruginosa	1.62	X-RAY DIFFRACTION	99.5
4ZAN	LYASE	04/13/15	Structure of UbiX Y169F in complex with oxidised FMN and dimethylallyl monophosphate	Pseudomonas aeruginosa	1.76	X-RAY DIFFRACTION	99.5
4ZAF	LYASE	04/13/15	Structure of UbiX in complex with oxidised FMN and dimethylallyl monophosphate	Pseudomonas aeruginosa	1.71	X-RAY DIFFRACTION	100.0
6QLJ	TRANSFERASE	02/01/19	Crystal structure of F181Q UbiX in complex with an oxidised N5-C1' adduct derived from DMAP	Pseudomonas aeruginosa	1.77	X-RAY DIFFRACTION	99.5
4ZAX	TRANSFERASE	04/14/15	Structure of UbiX in complex with oxidised prenylated FMN (radical)	Pseudomonas aeruginosa	1.61	X-RAY DIFFRACTION	100.0

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 371 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001664 (536 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_11860 Search term: aromatic acid decarboxylase

Human Homologs

References