Strain |
Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest |
Locus Tag |
PA14_12060
|
Name |
pbpA
|
Replicon | chromosome |
Genomic location | 1040914 - 1042854 (+ strand) |
Transposon Mutants | 1 transposon mutants in UCBPP-PA14 |
RefSeq | YP_789116.1 |
GI | 116052041 |
Entrez | 4383490 |
INSDC | ABJ13277.1 |
NCBI Locus Tag | PA14_12060 |
UniParc | UPI00000D4222 |
UniProtKB Acc | Q02SH0 |
UniProtKB ID | Q02SH0_PSEAB |
UniRef100 | UniRef100_G3XCV7 |
UniRef50 | UniRef50_G8PXZ8 |
UniRef90 | UniRef90_G3XCV7 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
penicillin-binding protein 2
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | 5.83 |
Kyte-Doolittle Hydrophobicity Value | -0.332 |
Molecular Weight (kDa) | 72.2 |
Isoelectric Point (pI) | 8.49 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
7KIS | HYDROLASE/Inhibitor/Antibiotic | 10/24/20 | Crystal structure of Pseudomonas aeruginosa PBP2 in complex with WCK 5153 | Pseudomonas aeruginosa | 2.869 | X-RAY DIFFRACTION | 100.0 |
Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.
Drug Name | Source Accession | Source DB | Version | Target Accession | Target Description | Percent Identity | Alignment Length | E-Value |
Ceftazidime | DB00438 | DrugBank | 5.1.4 | Q9X6V3 | Penicillin-binding protein 2 | 100.0 | 646 | 0.0e+00 |
Cefepime | DB01413 | DrugBank | 5.1.4 | Q9X6V3 | Penicillin-binding protein 2 | 100.0 | 646 | 0.0e+00 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 575 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001680 (534 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA14_12060
Search term: pbpA
Search term: penicillin-binding protein 2
|