Pseudomonas aeruginosa UCBPP-PA14, PA14_12230 (leuS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_12230
Name
leuS
Replicon chromosome
Genomic location 1055410 - 1058031 (- strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq YP_789131.1
GI 116052026
EC Number 6.1.1.4
Entrez 4382017
INSDC ABJ13262.1
NCBI Locus Tag PA14_12230
UniParc UPI0000396243
UniProtKB Acc Q02SF5
UniProtKB ID SYL_PSEAB
UniRef100 UniRef100_Q02SF5
UniRef50 UniRef50_Q9HX33
UniRef90 UniRef90_Q9HX33

Product

Feature Type CDS
Coding Frame 1
Product Name
leucyl-tRNA synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -21.02
Kyte-Doolittle Hydrophobicity Value -0.332
Molecular Weight (kDa) 97.6
Isoelectric Point (pI) 5.32

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 668 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001694 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_12230
Search term: leuS

Human Homologs

Ensembl 110, assembly GRCh38.p14
leucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:17095]
E-value: 2.8e-159
Percent Identity: 36.4
Ensembl 110, assembly GRCh38.p14
leucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:17095]
E-value: 2.8e-159
Percent Identity: 36.4
Ensembl 110, assembly GRCh38.p14
leucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:17095]
E-value: 2.8e-159
Percent Identity: 36.4

References

No references are associated with this feature.