Pseudomonas aeruginosa UCBPP-PA14, PA14_12850

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_12850
Name
Replicon	chromosome
Genomic location	1102625 - 1103203 (+ strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	1 transposon mutants in orthologs

Cross-References

RefSeq	YP_789173.1
GI	116051984
Entrez	4381992
INSDC	ABJ13220.1
NCBI Locus Tag	PA14_12850
UniParc	UPI0000396223
UniProtKB Acc	Q02SB3
UniProtKB ID	Q02SB3_PSEAB
UniRef100	UniRef100_V6AA79
UniRef50	UniRef50_J3E884
UniRef90	UniRef90_W0YZ18

Product

Feature Type	CDS
Coding Frame	1
Product Name	acetyltransferase
Synonyms
Evidence for Translation
Charge (pH 7)	-5.59
Kyte-Doolittle Hydrophobicity Value	-0.274
Molecular Weight (kDa)	21.9
Isoelectric Point (pI)	5.32

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
7KYE	TRANSFERASE	12/07/20	Structure of a GNAT superfamily PA3944 acetyltransferase in complex with CHES	Pseudomonas aeruginosa	1.93	X-RAY DIFFRACTION	99.5
7KPS	TRANSFERASE	11/12/20	Structure of a GNAT superfamily PA3944 acetyltransferase in complex with AcCoA	Pseudomonas aeruginosa	1.8	X-RAY DIFFRACTION	99.5
7KPP	TRANSFERASE	11/12/20	Structure of the E102A mutant of a GNAT superfamily PA3944 acetyltransferase	Pseudomonas aeruginosa	1.45	X-RAY DIFFRACTION	99.0
6EDD	TRANSFERASE	08/09/18	Crystal structure of a GNAT Superfamily PA3944 acetyltransferase in complex with CoA (P1 space group)	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	1.55	X-RAY DIFFRACTION	99.5
7KYJ	TRANSFERASE	12/07/20	Structure of a GNAT superfamily PA3944 acetyltransferase in complex with zinc	Pseudomonas aeruginosa	2	X-RAY DIFFRACTION	99.5
6EDV	TRANSFERASE	08/12/18	Structure of a GNAT superfamily acetyltransferase PA3944 in complex with CoA	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	1.35	X-RAY DIFFRACTION	99.5

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 295 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001732 (803 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_12850 Search term: acetyltransferase

Human Homologs

References