Pseudomonas aeruginosa UCBPP-PA14, PA14_14610 (yajC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_14610
Name
yajC
Replicon chromosome
Genomic location 1247147 - 1247485 (+ strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14

Cross-References

RefSeq YP_789310.1
GI 116051847
Entrez 4381892
INSDC ABJ13083.1
NCBI Locus Tag PA14_14610
UniParc UPI00000C5B29
UniProtKB Acc Q02RX6
UniProtKB ID Q02RX6_PSEAB
UniRef100 UniRef100_W0YVN4
UniRef50 UniRef50_Q4K6T0
UniRef90 UniRef90_M4X3P6

Product

Feature Type CDS
Coding Frame 1
Product Name
preprotein translocase subunit YajC
Synonyms
Evidence for Translation
Charge (pH 7) 2.22
Kyte-Doolittle Hydrophobicity Value 0.388
Molecular Weight (kDa) 11.9
Isoelectric Point (pI) 9.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
YajC YajC interacts with the AcrAB-TolC efflux pump in a way that in uncharacterized but is shown to grant increased fitness in the presence of linezolid, rifampicin, and vancomycin. [PMID:31871033] ARO:3005040 protein homolog model Perfect 217.2 100.0 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 453 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001844 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_14610
Search term: yajC

Human Homologs

References

No references are associated with this feature.