Pseudomonas aeruginosa UCBPP-PA14, PA14_14820 (ndk)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_14820
Name
ndk
Replicon chromosome
Genomic location 1259590 - 1260021 (+ strand)

Cross-References

RefSeq YP_789325.1
GI 116051832
Entrez 4381877
INSDC ABJ13068.1
NCBI Locus Tag PA14_14820
UniParc UPI000012FEBA
UniProtKB Acc Q02RW1
UniProtKB ID NDK_PSEAB
UniRef100 UniRef100_A6V0V6
UniRef50 UniRef50_Q5WGT0
UniRef90 UniRef90_A6V0V6

Product

Feature Type CDS
Coding Frame 1
Product Name
nucleoside diphosphate kinase
Synonyms
Evidence for Translation
Charge (pH 7) -2.55
Kyte-Doolittle Hydrophobicity Value -0.089
Molecular Weight (kDa) 15.6
Isoelectric Point (pI) 5.31

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6AES TRANSFERASE 08/06/18 Crystal structure of Nucleoside diphosphate kinase from Pseudomonas aeruginosa at 3.55 A resolution. Pseudomonas aeruginosa 3.55 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 598 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001859 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_14820
Search term: ndk

Human Homologs

Ensembl 110, assembly GRCh38.p14
NME/NM23 family member 7 [Source:HGNC Symbol;Acc:HGNC:20461]
E-value: 2.0e-22
Percent Identity: 41.7
Ensembl 110, assembly GRCh38.p14
NME/NM23 family member 7 [Source:HGNC Symbol;Acc:HGNC:20461]
E-value: 2.0e-22
Percent Identity: 41.7
Ensembl 110, assembly GRCh38.p14
NME/NM23 family member 7 [Source:HGNC Symbol;Acc:HGNC:20461]
E-value: 2.0e-22
Percent Identity: 41.7
Ensembl 110, assembly GRCh38.p14
NME/NM23 family member 7 [Source:HGNC Symbol;Acc:HGNC:20461]
E-value: 2.0e-22
Percent Identity: 41.7

References

No references are associated with this feature.