Pseudomonas aeruginosa UCBPP-PA14, PA14_14850 (pilF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_14850
Name
pilF
Replicon chromosome
Genomic location 1261203 - 1261961 (+ strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq YP_789327.1
GI 116051830
Entrez 4381875
INSDC ABJ13066.1
NCBI Locus Tag PA14_14850
UniParc UPI00003961BF
UniProtKB Acc Q02RV9
UniProtKB ID Q02RV9_PSEAB
UniRef100 UniRef100_W0YXI3
UniRef50 UniRef50_Q9HXJ2
UniRef90 UniRef90_Q9HXJ2

Product

Feature Type CDS
Coding Frame 1
Product Name
type 4 fimbrial biogenesis protein PilF
Synonyms
Evidence for Translation
Charge (pH 7) 0.21
Kyte-Doolittle Hydrophobicity Value -0.565
Molecular Weight (kDa) 28.5
Isoelectric Point (pI) 7.33

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2FI7 PROTEIN BINDING 12/28/05 Crystal Structure of PilF : Functional implication in the type 4 pilus biogenesis in Pseudomonas aeruginosa Pseudomonas aeruginosa 2.2 X-RAY DIFFRACTION 99.6
2HO1 PROTEIN BINDING 07/13/06 Functional Characterization of Pseudomonas Aeruginosa pilF Pseudomonas aeruginosa 2 X-RAY DIFFRACTION 99.6

Virulence Evidence

Source 1
Database Victors : 4412
Category
Evidence ECO:0000015
mutant phenotype evidence
Host Organism Mus musculus
Notes
Reference 18591226
Source 2
Database Victors : 4412
Category
Evidence ECO:0000015
mutant phenotype evidence
Host Organism Drosophila melanogaster
Notes
Reference 18591226
Source 3
Database PseudoCAP
Category
Evidence ECO:0000015
mutant phenotype evidence
Host Organism Caenorhabditis elegans
Notes
Infection model C. elegans slow killing assay.
Reference 22911607

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 206 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001861 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_14850
Search term: pilF

Human Homologs

References

No references are associated with this feature.