Pseudomonas aeruginosa UCBPP-PA14, PA14_15740 (purL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_15740
Name
purL
Replicon chromosome
Genomic location 1338564 - 1342460 (+ strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 7 transposon mutants in orthologs

Cross-References

RefSeq YP_789399.1
GI 116051762
EC Number 6.3.5.3
Entrez 4381298
INSDC ABJ12998.1
NCBI Locus Tag PA14_15740
UniParc UPI0000396184
UniProtKB Acc Q02RN7
UniProtKB ID Q02RN7_PSEAB
UniRef100 UniRef100_Q02RN7
UniRef50 UniRef50_P15254
UniRef90 UniRef90_Q9HXN2

Product

Feature Type CDS
Coding Frame 1
Product Name
phosphoribosylformylglycinamidine synthase
Synonyms
Evidence for Translation
Charge (pH 7) -47.15
Kyte-Doolittle Hydrophobicity Value -0.165
Molecular Weight (kDa) 140.7
Isoelectric Point (pI) 4.81

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 621 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001918 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_15740
Search term: purL

Human Homologs

Ensembl 110, assembly GRCh38.p14
phosphoribosylformylglycinamidine synthase [Source:HGNC Symbol;Acc:HGNC:8863]
E-value: 9.8e-225
Percent Identity: 36.6

References

No references are associated with this feature.