Pseudomonas aeruginosa UCBPP-PA14, PA14_16300

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_16300
Name
Replicon	chromosome
Genomic location	1392121 - 1392282 (+ strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	1 transposon mutants in orthologs

Cross-References

RefSeq	YP_789445.1
GI	116051716
Entrez	4380216
INSDC	ABJ12952.1
NCBI Locus Tag	PA14_16300
UniParc	UPI0000396166
UniProtKB Acc	Q02RJ1
UniProtKB ID	Q02RJ1_PSEAB
UniRef100	UniRef100_Q02RJ1
UniRef50	UniRef50_W0YX37
UniRef90	UniRef90_W0YX37

Product

Feature Type	CDS
Coding Frame	1
Product Name	hypothetical protein
Synonyms
Evidence for Translation
Charge (pH 7)	4.22
Kyte-Doolittle Hydrophobicity Value	-1.158
Molecular Weight (kDa)	6.1
Isoelectric Point (pI)	10.72

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown Class 3 20472543
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name	Definition	Accession	Model Type (?)	SNP	Cutoff	Bit Score	Percent Identity	CARD Version
ArmR	ArmR, a 53-amino-acid antirepressor, allosterically inhibits MexR dimer-DNA binding by occupying a hydrophobic binding cavity within the center of the MexR dimer. ArmR up-regulation and MexR-ArmR complex formation have previously been shown to upregulate MexAB-OprM. [PMID:17545281, PMID:18812515]	ARO:3004056	protein homolog model		Strict	105.1	98.11	3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
3ECH	Transcription, Transcription regulation	08/30/08	The MarR-family repressor MexR in complex with its antirepressor ArmR	Pseudomonas aeruginosa	1.802	X-RAY DIFFRACTION	100.0

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in one genus

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001964 (205 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_16300

Human Homologs

References