Pseudomonas aeruginosa UCBPP-PA14, PA14_16820

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_16820
Name
Replicon chromosome
Genomic location 1438753 - 1441830 (+ strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 8 transposon mutants in orthologs

Cross-References

RefSeq YP_789488.1
GI 116051673
Entrez 4381600
INSDC ABJ12909.1
NCBI Locus Tag PA14_16820
UniParc UPI0000396144
UniProtKB Acc Q02RE8
UniProtKB ID Q02RE8_PSEAB
UniRef100 UniRef100_S0I7M5
UniRef50 UniRef50_B7V2T7
UniRef90 UniRef90_B7V2T7

Product

Feature Type CDS
Coding Frame 1
Product Name
efflux transmembrane protein
Synonyms
Evidence for Translation
Charge (pH 7) -0.84
Kyte-Doolittle Hydrophobicity Value 0.234
Molecular Weight (kDa) 113.3
Isoelectric Point (pI) 6.87

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
MexK MexK is the inner membrane resistance-nodulation-cell division (RND) transporter in the MexJK multidrug efflux protein. [PMID:12193619] ARO:3003693 protein homolog model Strict 1945.2 99.8 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 487 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000156 (999 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_16820

Human Homologs

References

No references are associated with this feature.