Pseudomonas aeruginosa UCBPP-PA14, PA14_17420 (ispF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_17420
Name
ispF
Replicon chromosome
Genomic location 1495111 - 1495584 (+ strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq YP_789537.1
GI 116051624
EC Number 4.6.1.12
Entrez 4381590
INSDC ABJ12860.1
NCBI Locus Tag PA14_17420
UniParc UPI0000396120
UniProtKB Acc Q02R99
UniProtKB ID ISPF_PSEAB
UniRef100 UniRef100_Q02R99
UniRef50 UniRef50_Q5L8X2
UniRef90 UniRef90_A6V1G1

Product

Feature Type CDS
Coding Frame 1
Product Name
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Synonyms
Evidence for Translation
Charge (pH 7) 0.39
Kyte-Doolittle Hydrophobicity Value 0.057
Molecular Weight (kDa) 16.6
Isoelectric Point (pI) 7.10

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5B8F LYASE 04/20/15 X-ray Crystal Structure of a 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Pseudomonas aeruginosa Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) 1.45 X-RAY DIFFRACTION 99.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 520 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002047 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_17420
Search term: ispF

Human Homologs

References

No references are associated with this feature.