Pseudomonas aeruginosa UCBPP-PA14, PA14_17900 (metR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_17900
Name
metR
Replicon chromosome
Genomic location 1537346 - 1538266 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_789577.1
GI 116051585
Entrez 4381551
INSDC ABJ12821.1
NCBI Locus Tag PA14_17900
UniParc UPI0000396107
UniProtKB Acc Q02R59
UniProtKB ID Q02R59_PSEAB
UniRef100 UniRef100_W0YXW0
UniRef50 UniRef50_Q4K712
UniRef90 UniRef90_Q9HY39

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator MetR
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -6.22
Kyte-Doolittle Hydrophobicity Value 0.047
Molecular Weight (kDa) 34.2
Isoelectric Point (pI) 5.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 520 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002083 (533 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_17900
Search term: metR

Human Homologs

References

Swarming of Pseudomonas aeruginosa is controlled by a broad spectrum of transcriptional regulators, including MetR.
Yeung AT, Torfs EC, Jamshidi F, Bains M, Wiegand I, Hancock RE, Overhage J
J Bacteriol 2009 Sep;191(18):5592-602
PubMed ID: 19592586