Pseudomonas aeruginosa UCBPP-PA14, PA14_45940 (lasI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_45940
Name
lasI
Replicon chromosome
Genomic location 4084370 - 4084975 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq YP_791820.1
GI 116049377
Entrez 4382866
INSDC ABJ10613.1
NCBI Locus Tag PA14_45940
UniParc UPI000012E230
UniProtKB Acc Q02JR6
UniProtKB ID Q02JR6_PSEAB
UniRef100 UniRef100_P33883
UniRef50 UniRef50_P33883
UniRef90 UniRef90_P33883

Product

Feature Type CDS
Coding Frame 1
Product Name
autoinducer synthesis protein LasI
Synonyms
Evidence for Translation
Charge (pH 7) -1.13
Kyte-Doolittle Hydrophobicity Value -0.104
Molecular Weight (kDa) 22.7
Isoelectric Point (pI) 6.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
1RO5 SIGNALING PROTEIN 12/01/03 Crystal Structure of the AHL Synthase LasI PSEUDOMONAS AERUGINOSA 2.3 X-RAY DIFFRACTION 98.0

Virulence Evidence

Source 1
Database PseudoCAP
Category
Evidence ECO:0000015
mutant phenotype evidence
Host Organism Caenorhabditis elegans
Notes
Infection model C. elegans slow killing assay.
Reference 22911607

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 58 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001349 (307 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_45940
Search term: lasI

References

No references are associated with this feature.