Pseudomonas aeruginosa UCBPP-PA14, PA14_50730 (shaF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_50730
Name
shaF
Replicon chromosome
Genomic location 4505067 - 4507868 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_792215.1
GI 116048983
Entrez 4384763
INSDC ABJ10219.1
NCBI Locus Tag PA14_50730
UniParc UPI00003965BA
UniProtKB Acc Q02IM1
UniProtKB ID Q02IM1_PSEAB
UniRef100 UniRef100_A0A022P8G3
UniRef50 UniRef50_Q47XI9
UniRef90 UniRef90_W0WIV0

Product

Feature Type CDS
Coding Frame 1
Product Name
ShaF
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 3.72
Kyte-Doolittle Hydrophobicity Value 0.926
Molecular Weight (kDa) 99.6
Isoelectric Point (pI) 7.59

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 564 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001016 (1084 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_50730
Search term: shaF
Search term: ShaF

Human Homologs

Ensembl 94, assembly GRCh38.p12
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 [Source:HGNC Symbol;Acc:HGNC:7461]
E-value: 2.8e-41
Percent Identity: 33.6

References

Characterization of a multigene-encoded sodium/hydrogen antiporter (sha) from Pseudomonas aeruginosa: its involvement in pathogenesis.
Kosono S, Haga K, Tomizawa R, Kajiyama Y, Hatano K, Takeda S, Wakai Y, Hino M, Kudo T
J. Bacteriol. 2005 Aug;187(15):5242-8
PubMed ID: 16030218