Pseudomonas aeruginosa UCBPP-PA14, PA14_51780 (ruvB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_51780
Name
ruvB
Replicon chromosome
Genomic location 4598188 - 4599246 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq YP_792307.1
GI 116048892
EC Number 3.1.22.4
Entrez 4384455
INSDC ABJ10128.1
NCBI Locus Tag PA14_51780
UniParc UPI000013538A
UniProtKB Acc Q02IC9
UniProtKB ID RUVB_PSEAB
UniRef100 UniRef100_B7UXW5
UniRef50 UniRef50_Q5SL87
UniRef90 UniRef90_A6VA05

Product

Feature Type CDS
Coding Frame 1
Product Name
Holliday junction DNA helicase RuvB
Synonyms
Evidence for Translation
Charge (pH 7) -8.30
Kyte-Doolittle Hydrophobicity Value -0.141
Molecular Weight (kDa) 38.9
Isoelectric Point (pI) 5.18

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6BLB HYDROLASE 11/09/17 1.88 Angstrom Resolution Crystal Structure Holliday Junction ATP-dependent DNA Helicase (RuvB) from Pseudomonas aeruginosa in Complex with ADP PSEUDOMONAS AERUGINOSA (STRAIN ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PR 1.88 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 590 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000932 (552 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_51780
Search term: ruvB

Human Homologs

Ensembl 94, assembly GRCh38.p12
Werner helicase interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:20876]
E-value: 2.8e-05
Percent Identity: 25.4

References

No references are associated with this feature.