Pseudomonas aeruginosa UCBPP-PA14, PA14_55130 (gloA2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_55130
Name
gloA2
Replicon chromosome
Genomic location 4897432 - 4897827 (- strand)
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_792584.1
GI 116048617
Entrez 4384884
INSDC ABJ09853.1
NCBI Locus Tag PA14_55130
UniParc UPI000039649C
UniProtKB Acc Q02HK2
UniProtKB ID Q02HK2_PSEAB
UniRef100 UniRef100_Q02HK2
UniRef50 UniRef50_W6M5E2
UniRef90 UniRef90_Q9I5L8

Product

Feature Type CDS
Coding Frame 1
Product Name
lactoylglutathione lyase
Synonyms
Evidence for Translation
Charge (pH 7) -3.08
Kyte-Doolittle Hydrophobicity Value -0.405
Molecular Weight (kDa) 14.9
Isoelectric Point (pI) 5.64

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4MTR LYASE 09/20/13 Zn-bound GloA2 PSEUDOMONAS AERUGINOSA 1.83 X-RAY DIFFRACTION 99.2
4MTT LYASE 09/20/13 Ni- and Zn-bound GloA2 at low resolution PSEUDOMONAS AERUGINOSA 2.17 X-RAY DIFFRACTION 99.2
4MTS LYASE 09/20/13 Ni- and Zn-bound GloA2 at high resolution PSEUDOMONAS AERUGINOSA 1.8 X-RAY DIFFRACTION 99.2
4MTQ LYASE 09/20/13 Ni-bound GloA2 PSEUDOMONAS AERUGINOSA 2.17 X-RAY DIFFRACTION 99.2

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 323 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000687 (304 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_55130
Search term: gloA2

Human Homologs

Ensembl 94, assembly GRCh38.p12
glyoxalase I [Source:HGNC Symbol;Acc:HGNC:4323]
E-value: 2.2e-16
Percent Identity: 34.3

References

No references are associated with this feature.