Pseudomonas aeruginosa UCBPP-PA14, PA14_57160 (apbA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_57160
Name
apbA
Replicon chromosome
Genomic location 5090592 - 5091503 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_792743.1
GI 116052432
EC Number 1.1.1.169
Entrez 4382502
INSDC ABJ13668.1
NCBI Locus Tag PA14_57160
UniParc UPI000039636C
UniProtKB Acc Q02H43
UniProtKB ID Q02H43_PSEAB
UniRef100 UniRef100_Q02H43
UniRef50 UniRef50_Q9HW09
UniRef90 UniRef90_Q9HW09

Product

Feature Type CDS
Coding Frame 1
Product Name
2-dehydropantoate 2-reductase
Synonyms
Evidence for Translation
Charge (pH 7) 6.46
Kyte-Doolittle Hydrophobicity Value -0.206
Molecular Weight (kDa) 33.0
Isoelectric Point (pI) 8.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5ZIK OXIDOREDUCTASE 03/16/18 Crystal structure of Ketopantoate reductase from Pseudomonas aeruginosa Pseudomonas aeruginosa PAO1 2.45 X-RAY DIFFRACTION 98.7
5ZIX OXIDOREDUCTASE 03/17/18 Crystal structure of Ketopantoate reductase from Pseudomonas aeruginosa bound to NADP+ Pseudomonas aeruginosa PAO1 2.57 X-RAY DIFFRACTION 98.7
6K1R OXIDOREDUCTASE 05/12/19 Crystal structure of Ketopantoate reductase from Pseudomonas aeruginosa in complex with NAD+ and ketopantoate Pseudomonas aeruginosa PAO1 2.55 X-RAY DIFFRACTION 98.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 290 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003987 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_57160
Search term: apbA

Human Homologs

References

No references are associated with this feature.