Pseudomonas aeruginosa UCBPP-PA14, PA14_57170

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_57170
Name
Replicon chromosome
Genomic location 5091554 - 5093650 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq YP_792744.1
GI 116052433
Entrez 4382503
INSDC ABJ13669.1
NCBI Locus Tag PA14_57170
UniParc UPI000039636D
UniProtKB Acc Q02H42
UniProtKB ID Q02H42_PSEAB
UniRef100 UniRef100_Q02H42
UniRef50 UniRef50_Q4K7C5
UniRef90 UniRef90_Q02H42

Product

Feature Type CDS
Coding Frame 1
Product Name
two-component sensor
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -9.88
Kyte-Doolittle Hydrophobicity Value -0.212
Molecular Weight (kDa) 77.6
Isoelectric Point (pI) 5.71

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 590 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003988 (532 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_57170

Human Homologs

References

Sensor kinase PA4398 modulates swarming motility and biofilm formation in Pseudomonas aeruginosa PA14.
Strehmel J, Neidig A, Nusser M, Geffers R, Brenner-Weiss G, Overhage J
Appl Environ Microbiol 2015 Feb;81(4):1274-85
PubMed ID: 25501476