Pseudomonas aeruginosa UCBPP-PA14, PA14_58470 (dppD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_58470
Name
dppD
Replicon chromosome
Genomic location 5207642 - 5208616 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq YP_792850.1
GI 116052536
Entrez 4382626
INSDC ABJ13772.1
NCBI Locus Tag PA14_58470
UniParc UPI00003963B2
UniProtKB Acc Q02GT6
UniProtKB ID Q02GT6_PSEAB
UniRef100 UniRef100_A0A069PYH4
UniRef50 UniRef50_Q4KIC6
UniRef90 UniRef90_A0A069PYH4

Product

Feature Type CDS
Coding Frame 1
Product Name
dipeptide ABC transporter ATP-binding protein DppD
Product Name Confidence: Class 1
Synonyms ABC transporter ATP-binding protein
Evidence for Translation
Charge (pH 7) -5.01
Kyte-Doolittle Hydrophobicity Value 0.052
Molecular Weight (kDa) 35.4
Isoelectric Point (pI) 6.05

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004092 (509 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_58470
Search term: dppD

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily B member 10 [Source:HGNC Symbol;Acc:HGNC:41]
E-value: 9.2e-15
Percent Identity: 28.4

References

High-throughput screening of dipeptide utilization mediated by the ABC transporter DppBCDF and its substrate-binding proteins DppA1-A5 in Pseudomonas aeruginosa.
Pletzer D, Lafon C, Braun Y, Köhler T, Page MG, Mourez M, Weingart H
PLoS One 2014;9(10):e111311
PubMed ID: 25338022