Strain |
Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest |
Locus Tag |
PA14_62000
|
Name |
hitA
|
Replicon | chromosome |
Genomic location | 5529629 - 5530636 (+ strand) |
Transposon Mutants | 1 transposon mutants in UCBPP-PA14 |
Transposon Mutants in orthologs | 5 transposon mutants in orthologs |
RefSeq | YP_793149.1 |
GI | 116052832 |
Entrez | 4384625 |
INSDC | ABJ14068.1 |
NCBI Locus Tag | PA14_62000 |
UniParc | UPI00000C5DC7 |
UniProtKB Acc | Q02FY7 |
UniProtKB ID | Q02FY7_PSEAB |
UniRef100 | UniRef100_W0YXB5 |
UniRef50 | UniRef50_V6JBE1 |
UniRef90 | UniRef90_A6VCD9 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
ferric iron-binding periplasmic protein HitA
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -4.82 |
Kyte-Doolittle Hydrophobicity Value | -0.223 |
Molecular Weight (kDa) | 36.1 |
Isoelectric Point (pI) | 5.48 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
6IVY | STRUCTURAL PROTEIN | 12/04/18 | Crystal structure of iron-bound HitA from Pseudomonas aeruginosa | Pseudomonas aeruginosa PAO1 | 2 | X-RAY DIFFRACTION | 100.0 |
6IWF | METAL BINDING PROTEIN | 12/05/18 | Crystal structure of HitA from Pseudomonas aeruginosa | Pseudomonas aeruginosa PAO1 | 1.70662 | X-RAY DIFFRACTION | 100.0 |
6J2S | METAL BINDING PROTEIN | 01/02/19 | Structure of HitA bound to gallium from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 1.73005 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 314 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004337 (456 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA14_62000
Search term: hitA
Search term: ferric iron-binding periplasmic protein HitA
|
Isolation and characterization of gallium resistant Pseudomonas aeruginosa mutants.
García-Contreras R, Lira-Silva E, Jasso-Chávez R, Hernández-González IL, Maeda T, Hashimoto T, Boogerd FC, Sheng L, Wood TK, Moreno-Sánchez R
Int J Med Microbiol 2013 Dec;303(8):574-82
PubMed ID: 23992635
|
Immunization with the ferric iron-binding periplasmic protein HitA provides protection against Pseudomonas aeruginosa in the murine infection model.
Elhosary MA, Bahey-El-Din M, AbdelBary A, El Guink N, Aboushleib HM
Microb Pathog 2019 Jun;131:181-185
PubMed ID: 30978430
|