Pseudomonas aeruginosa UCBPP-PA14, PA14_62910 (carB)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_62910
Name	carB
Replicon	chromosome
Genomic location	5611793 - 5615014 (- strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	3 transposon mutants in orthologs

Cross-References

RefSeq	YP_793220.1
GI	116052903
EC Number	6.3.5.5
Entrez	4383205
INSDC	ABJ14139.1
NCBI Locus Tag	PA14_62910
UniParc	UPI0000165ED6
UniProtKB Acc	Q02FR6
UniProtKB ID	Q02FR6_PSEAB
UniRef100	UniRef100_P38100
UniRef50	UniRef50_P00968
UniRef90	UniRef90_P38100

Product

Feature Type	CDS
Coding Frame	1
Product Name	carbamoyl phosphate synthase large subunit
Synonyms
Evidence for Translation
Charge (pH 7)	-33.47
Kyte-Doolittle Hydrophobicity Value	-0.096
Molecular Weight (kDa)	117.3
Isoelectric Point (pI)	4.78

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 624 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG004401 (534 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_62910 Search term: carB Search term: carbamoyl phosphate synthase large subunit

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000501073 carbamoyl-phosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:2323] E-value: 6.6e-227 Percent Identity: 40.8
Ensembl 110, assembly GRCh38.p14	ENSP00000233072 carbamoyl-phosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:2323] E-value: 6.6e-227 Percent Identity: 40.8
Ensembl 110, assembly GRCh38.p14	ENSP00000402608 carbamoyl-phosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:2323] E-value: 6.6e-227 Percent Identity: 40.8
Ensembl 110, assembly GRCh38.p14	ENSP00000501022 carbamoyl-phosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:2323] E-value: 6.6e-227 Percent Identity: 40.8
Ensembl 110, assembly GRCh38.p14	ENSP00000500537 carbamoyl-phosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:2323] E-value: 6.6e-227 Percent Identity: 40.8

References