Pseudomonas aeruginosa UCBPP-PA14, PA14_64220 (purD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_64220
Name
purD
Replicon chromosome
Genomic location 5721422 - 5722711 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_793321.1
GI 116053003
EC Number 6.3.4.13
Entrez 4383324
INSDC ABJ14239.1
NCBI Locus Tag PA14_64220
UniParc UPI0000396EDC
UniProtKB Acc Q02FG5
UniProtKB ID Q02FG5_PSEAB
UniRef100 UniRef100_Q02FG5
UniRef50 UniRef50_P26977
UniRef90 UniRef90_Q9HUV8

Product

Feature Type CDS
Coding Frame 1
Product Name
phosphoribosylamine--glycine ligase
Synonyms
Evidence for Translation
Charge (pH 7) -13.90
Kyte-Doolittle Hydrophobicity Value 0.054
Molecular Weight (kDa) 45.2
Isoelectric Point (pI) 4.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 627 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004484 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_64220
Search term: purD

Human Homologs

Ensembl 110, assembly GRCh38.p14
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:HGNC Symbol;Acc:HGNC:4163]
E-value: 4.7e-115
Percent Identity: 52.8
Ensembl 110, assembly GRCh38.p14
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:HGNC Symbol;Acc:HGNC:4163]
E-value: 4.7e-115
Percent Identity: 52.8
Ensembl 110, assembly GRCh38.p14
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:HGNC Symbol;Acc:HGNC:4163]
E-value: 4.7e-115
Percent Identity: 52.8
Ensembl 110, assembly GRCh38.p14
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:HGNC Symbol;Acc:HGNC:4163]
E-value: 4.7e-115
Percent Identity: 52.8

References

No references are associated with this feature.