Pseudomonas aeruginosa UCBPP-PA14, PA14_65310 (hfq)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_65310
Name
hfq
Replicon chromosome
Genomic location 5819787 - 5820035 (- strand)

Cross-References

RefSeq YP_793412.1
GI 116053093
Entrez 4384847
INSDC ABJ14329.1
NCBI Locus Tag PA14_65310
UniParc UPI000012C6A3
UniProtKB Acc Q02F74
UniProtKB ID HFQ_PSEAB
UniRef100 UniRef100_A6VD57
UniRef50 UniRef50_Q9ZI76
UniRef90 UniRef90_Q4KJ73

Product

Feature Type CDS
Coding Frame 1
Product Name
RNA-binding protein Hfq
Synonyms
Evidence for Translation
Charge (pH 7) 3.46
Kyte-Doolittle Hydrophobicity Value -0.244
Molecular Weight (kDa) 9.1
Isoelectric Point (pI) 10.00

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3QUI RNA BINDING PROTEIN 02/24/11 Crystal structure of Pseudomonas aeruginosa Hfq in complex with ADPNP Pseudomonas aeruginosa 1.933 X-RAY DIFFRACTION 100.0
4J5Y RNA BINDING PROTEIN 02/11/13 Crystal structure of Hfq from Pseudomonas aeruginosa in complex with ATP Pseudomonas aeruginosa 2.0953 X-RAY DIFFRACTION 100.0
8BVH RNA BINDING PROTEIN 12/03/22 Cryo-EM structure of the Hfq-Crc-amiE translation repression assembly. Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT 3.6 ELECTRON MICROSCOPY 100.0
8BVJ RNA BINDING PROTEIN 12/04/22 Hfq-Crc-estA translation repression complex Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT 4.5 ELECTRON MICROSCOPY 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 282 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004559 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_65310
Search term: hfq

Human Homologs

References

No references are associated with this feature.