Pseudomonas aeruginosa UCBPP-PA14, PA14_66640 (pilO)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_66640
Name
pilO
Replicon chromosome
Genomic location 5949823 - 5950446 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 7 transposon mutants in orthologs

Cross-References

RefSeq YP_793511.1
GI 116053190
Entrez 4385525
INSDC ABJ14426.1
NCBI Locus Tag PA14_66640
UniParc UPI000045D4FB
UniProtKB Acc Q02EX5
UniProtKB ID Q02EX5_PSEAB
UniRef100 UniRef100_Q02EX5
UniRef50 UniRef50_Q4KJJ2
UniRef90 UniRef90_Q02EX5

Product

Feature Type CDS
Coding Frame 1
Product Name
type 4 fimbrial biogenesis protein PilO
Synonyms
Evidence for Translation
Charge (pH 7) -5.31
Kyte-Doolittle Hydrophobicity Value -0.078
Molecular Weight (kDa) 23.0
Isoelectric Point (pI) 4.91

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5UVR MEMBRANE PROTEIN 02/20/17 The core region of PilO from the type IV pilus system of Pseudomonas aeruginosa Pseudomonas aeruginosa 1.7 X-RAY DIFFRACTION 94.9
2RJZ STRUCTURAL GENOMICS, UNKNOWN FUNCTION 10/16/07 Crystal structure of the type 4 fimbrial biogenesis protein PilO from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.2 X-RAY DIFFRACTION 95.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 111 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004645 (941 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_66640
Search term: pilO

Human Homologs

References

No references are associated with this feature.