Pseudomonas aeruginosa UCBPP-PA14, PA14_70270 (algC)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_70270
Name	algC
Replicon	chromosome
Genomic location	6264129 - 6266693 (+ strand)
Transposon Mutants in orthologs	1 transposon mutants in orthologs

Cross-References

RefSeq	YP_793796.1
GI	116053469
Entrez	4384024
INSDC	ABJ14705.1
NCBI Locus Tag	PA14_70270
UniParc	UPI0000165EDE
UniProtKB Acc	Q02E40
UniProtKB ID	ALGC_PSEAB
UniRef100	UniRef100_Q02E40
UniRef50	UniRef50_Q02E40
UniRef90	UniRef90_Q02E40

Product

Feature Type	CDS
Coding Frame	1
Product Name	phosphomannomutase
Synonyms
Evidence for Translation
Charge (pH 7)	-16.00
Kyte-Doolittle Hydrophobicity Value	-0.056
Molecular Weight (kDa)	90946.9
Isoelectric Point (pI)	4.98

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown (This protein may have multiple localization sites) Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
1P5G	ISOMERASE	04/26/03	Enzyme-ligand complex of P. aeruginosa PMM/PGM	Pseudomonas aeruginosa	1.61	X-RAY DIFFRACTION	100.0
1P5D	ISOMERASE	04/25/03	Enzyme-ligand complex of P. aeruginosa PMM/PGM	Pseudomonas aeruginosa	1.6	X-RAY DIFFRACTION	100.0
2H5A	ISOMERASE	05/25/06	Complex of the enzyme PMM/PGM with xylose 1-phosphate	Pseudomonas aeruginosa	1.72	X-RAY DIFFRACTION	99.8
4IL8	ISOMERASE	12/29/12	Crystal structure of an H329A mutant of p. aeruginosa PMM/PGM	Pseudomonas aeruginosa	1.8	X-RAY DIFFRACTION	99.6
1PCM	ISOMERASE	05/16/03	Enzyme-ligand complex of P. aeruginosa PMM/PGM	Pseudomonas aeruginosa	1.9	X-RAY DIFFRACTION	100.0
3RSM	ISOMERASE	05/02/11	Crystal structure of S108C mutant of PMM/PGM	Pseudomonas aeruginosa	2.1	X-RAY DIFFRACTION	99.6
3C04	ISOMERASE	01/18/08	Structure of the P368G mutant of PMM/PGM from P. aeruginosa	Pseudomonas aeruginosa	2.2	X-RAY DIFFRACTION	99.8
3BKQ	ISOMERASE	12/07/07	Structure of the P368G mutant of PMM/PGM in complex with its substrate	Pseudomonas aeruginosa	2.05	X-RAY DIFFRACTION	99.8
2FKM	ISOMERASE	01/04/06	PMM/PGM S108D mutant with alpha-d-glucose 1,6-bisphosphate bound	Pseudomonas aeruginosa	1.9	X-RAY DIFFRACTION	99.8
1PCJ	ISOMERASE	05/16/03	Enzyme-ligand complex of P. aeruginosa PMM/PGM	Pseudomonas aeruginosa	2	X-RAY DIFFRACTION	100.0
4MRQ	ISOMERASE	09/17/13	Crystal Structure of wild-type unphosphorylated PMM/PGM	Pseudomonas aeruginosa	1.9	X-RAY DIFFRACTION	100.0
2H4L	ISOMERASE	05/24/06	Complex of PMM/PGM with ribose 1-phosphate	Pseudomonas aeruginosa	2.4	X-RAY DIFFRACTION	99.8
2FKF	ISOMERASE	01/04/06	Phosphomannomutase/Phosphoglucomutase from Pseudomonas aeruginosa with alpha-D-glucose 1,6-bisphosphate bound	Pseudomonas aeruginosa	2	X-RAY DIFFRACTION	100.0
1K35	ISOMERASE	10/01/01	Crystal Structure of Phosphomannomutase/Phosphoglucomutase from P.aeruginosa	Pseudomonas aeruginosa	2.2	X-RAY DIFFRACTION	100.0
1K2Y	ISOMERASE	09/30/01	Crystal Structure of Phosphomannomutase/Phosphoglucomutase S108A mutant from P. aeruginosa	Pseudomonas aeruginosa	1.75	X-RAY DIFFRACTION	99.8

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 660 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG004893 (536 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_70270 Search term: algC Search term: phosphomannomutase

Human Homologs

References