Pseudomonas aeruginosa UCBPP-PA14, PA14_72390

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_72390
Name
Replicon chromosome
Genomic location 6447605 - 6449392 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq YP_793961.1
GI 116053634
Entrez 4385153
INSDC ABJ14870.1
NCBI Locus Tag PA14_72390
UniParc UPI000045D337
UniProtKB Acc Q02DM5
UniProtKB ID Q02DM5_PSEAB
UniRef100 UniRef100_Q02DM5
UniRef50 UniRef50_O34206
UniRef90 UniRef90_O34206

Product

Feature Type CDS
Coding Frame 1
Product Name
two-component sensor
Synonyms
Evidence for Translation
Charge (pH 7) -8.65
Kyte-Doolittle Hydrophobicity Value -0.101
Molecular Weight (kDa) 66.0
Isoelectric Point (pI) 5.93

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4LLE TRANSFERASE 07/09/13 The crystal structure of R60L mutant of the histidine kinase (KinB) sensor domain from Pseudomonas aeruginosa PA01 PSEUDOMONAS AERUGINOSA 1.68 X-RAY DIFFRACTION 94.5
4LLC TRANSFERASE 07/09/13 The crystal structure of R60E mutant of the histidine kinase (KinB) sensor domain from Pseudomonas aeruginosa PA01 PSEUDOMONAS AERUGINOSA 2.0 X-RAY DIFFRACTION 94.5
3KKB TRANSFERASE 11/05/09 The crystal structure of a two-component sensor domain from Pseudomonas aeruginosa PA01 PSEUDOMONAS AERUGINOSA PAO1 1.881 X-RAY DIFFRACTION 95.3
3L34 TRANSFERASE 12/16/09 The crystal structure of a two-component sensor domain (2nd form) from Pseudomonas aeruginosa PA01 PSEUDOMONAS AERUGINOSA 1.7 X-RAY DIFFRACTION 95.3
3N24 TRANSFERASE 05/17/10 The crystal structure of a two-component sensor domain (3rd form) from Pseudomonas aeruginosa PA01 PSEUDOMONAS AERUGINOSA 2.056 X-RAY DIFFRACTION 95.3

Virulence Evidence

Source 1
Database PseudoCAP
Category
Evidence ECO:0000314
direct assay evidence used in manual assertion
Host Organism Danio rerio
Notes
Infection model Zebrafish embryo survival
Reference 21971182
Source 2
Database PseudoCAP
Category
Evidence ECO:0000015
mutant phenotype evidence
Host Organism Caenorhabditis elegans
Notes
Infection model C. elegans slow killing assay.
Reference 22911607

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 622 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005024 (547 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_72390

References

No references are associated with this feature.