Pseudomonas aeruginosa PAO1, PA1904 (phzF2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1904
Name
phzF2
Replicon chromosome
Genomic location 2075452 - 2076288 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_250595.1
GI 15597101
Affymetrix PA1904_s_at
DNASU PaCD00006857
Entrez 879183
GenBank AAG05293.1
NCBI Locus Tag PA1904
protein_id(GenBank) gb|AAG05293.1|AE004616_7|gnl|PseudoCAP|PA1904
TIGR NTL03PA01905
UniProtKB Acc O69754
UniProtKB ID PHZF_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
probable phenazine biosynthesis protein
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -2.96
Kyte-Doolittle Hydrophobicity Value -0.108
Molecular Weight (kDa) 30.3
Isoelectric Point (pI) 6.42

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB
Category Phenazine biosynthesis
Evidence
Host Organism
Notes
Reference

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 330 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001492 (429 members)
Putative Inparalogs 1 predicted inparalogs
probable phenazine biosynthesis protein (PA4215) 100.0% identity

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1904
Search term: phzF2

Human Homologs

Ensembl 110, assembly GRCh38.p14
phenazine biosynthesis like protein domain containing [Source:HGNC Symbol;Acc:HGNC:23301]
E-value: 1.2e-10
Percent Identity: 28.0
Ensembl 110, assembly GRCh38.p14
phenazine biosynthesis like protein domain containing [Source:HGNC Symbol;Acc:HGNC:23301]
E-value: 1.2e-10
Percent Identity: 28.0
Ensembl 110, assembly GRCh38.p14
phenazine biosynthesis like protein domain containing [Source:HGNC Symbol;Acc:HGNC:23301]
E-value: 1.2e-10
Percent Identity: 28.0

References

Functional analysis of genes for biosynthesis of pyocyanin and phenazine-1-carboxamide from Pseudomonas aeruginosa PAO1.
Mavrodi DV, Bonsall RF, Delaney SM, Soule MJ, Phillips G, Thomashow LS
J Bacteriol 2001 Nov;183(21):6454-65
PubMed ID: 11591691
Molecular analysis of genes encoding phenazine biosynthesis in the biological control bacterium. Pseudomonas aureofaciens 30-84.
Pierson LS 3rd, Gaffney T, Lam S, Gong F
FEMS Microbiol Lett 1995 Dec 15;134(2-3):299-307
PubMed ID: 8586283