Pseudomonas aeruginosa PAO1, PA3570 (mmsA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3570
Name
mmsA
Replicon chromosome
Genomic location 4002108 - 4003601 (- strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252260.1
GI 15598766
Affymetrix PA3570_mmsA_at
Entrez 878814
GenBank AAG06958.1
INSDC AAG06958.1
NCBI Locus Tag PA3570
protein_id(GenBank) gb|AAG06958.1|AE004778_2|gnl|PseudoCAP|PA3570
TIGR NTL03PA03570
UniParc UPI0000165ED2
UniProtKB Acc P28810
UniProtKB ID MMSA_PSEAE
UniRef100 UniRef100_P28810
UniRef50 UniRef50_P28810
UniRef90 UniRef90_P28810

Product

Feature Type CDS
Coding Frame 1
Product Name
methylmalonate-semialdehyde dehydrogenase
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.28
Kyte-Doolittle Hydrophobicity Value 0.031
Molecular Weight (kDa) 53.7
Isoelectric Point (pI) 6.38

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 594 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000721 (824 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3570
Search term: mmsA

Human Homologs

Ensembl 110, assembly GRCh38.p14
aldehyde dehydrogenase 6 family member A1 [Source:HGNC Symbol;Acc:HGNC:7179]
E-value: 2.2e-145
Percent Identity: 51.6

References

No references are associated with this feature.