Pseudomonas aeruginosa PAO1, PA3573

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3573
Name
Replicon chromosome
Genomic location 4004967 - 4006145 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252263.1
GI 15598769
Affymetrix PA3573_at
Entrez 878819
GenBank AAG06961.1
INSDC AAG06961.1
NCBI Locus Tag PA3573
protein_id(GenBank) gb|AAG06961.1|AE004778_5|gnl|PseudoCAP|PA3573
TIGR NTL03PA03573
UniParc UPI00000C5A73
UniProtKB Acc Q9HY47
UniProtKB ID Q9HY47_PSEAE
UniRef100 UniRef100_A0A022NW95
UniRef50 UniRef50_Q3KIJ8
UniRef90 UniRef90_A6V1M0

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 5.67
Kyte-Doolittle Hydrophobicity Value 0.873
Molecular Weight (kDa) 40.9
Isoelectric Point (pI) 8.47

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 499 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002096 (531 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3573

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Cloning and sequence analysis of an Escherichia coli gene conferring bicyclomycin resistance.
Bentley J, Hyatt LS, Ainley K, Parish JH, Herbert RB, White GR
Gene 1993 May 15;127(1):117-20
PubMed ID: 8486276