Pseudomonas aeruginosa PAO1, PA3590

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3590
Name
Replicon chromosome
Genomic location 4023200 - 4024732 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_252280.1
GI 15598786
Affymetrix PA3590_at
Entrez 880207
GenBank AAG06978.1
INSDC AAG06978.1
NCBI Locus Tag PA3590
protein_id(GenBank) gb|AAG06978.1|AE004779_10|gnl|PseudoCAP|PA3590
TIGR NTL03PA03590
UniParc UPI00000C5A7D
UniProtKB Acc Q9HY36
UniProtKB ID Q9HY36_PSEAE
UniRef100 UniRef100_Q9HY36
UniRef50 UniRef50_A0A069PH82
UniRef90 UniRef90_A0A077JWH3

Product

Feature Type CDS
Coding Frame 1
Product Name
probable hydroxyacyl-CoA dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -2.30
Kyte-Doolittle Hydrophobicity Value 0.166
Molecular Weight (kDa) 54.6
Isoelectric Point (pI) 6.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 444 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002080 (686 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3590

Human Homologs

Ensembl 110, assembly GRCh38.p14
hydroxyacyl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4799]
E-value: 4.9e-47
Percent Identity: 38.7

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295