Pseudomonas aeruginosa PAO1, PA3595

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3595
Name
Replicon chromosome
Genomic location 4029759 - 4031168 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252285.1
GI 15598791
Affymetrix PA3595_at
Entrez 880129
GenBank AAG06983.1
INSDC AAG06983.1
NCBI Locus Tag PA3595
protein_id(GenBank) gb|AAG06983.1|AE004780_2|gnl|PseudoCAP|PA3595
TIGR NTL03PA03595
UniParc UPI00000C5A82
UniProtKB Acc Q9HY31
UniProtKB ID Q9HY31_PSEAE
UniRef100 UniRef100_X6ZAS5
UniRef50 UniRef50_U5NZQ7
UniRef90 UniRef90_A6V1J5

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 12.25
Kyte-Doolittle Hydrophobicity Value 0.712
Molecular Weight (kDa) 50.1
Isoelectric Point (pI) 9.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 306 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002076 (336 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3595

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
A set of ordered cosmids and a detailed genetic and physical map for the 8 Mb Streptomyces coelicolor A3(2) chromosome.
Redenbach M, Kieser HM, Denapaite D, Eichner A, Cullum J, Kinashi H, Hopwood DA
Mol Microbiol 1996 Jul;21(1):77-96
PubMed ID: 8843436