Pseudomonas aeruginosa PAO1, PA3597

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3597
Name
Replicon chromosome
Genomic location 4032328 - 4033650 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 10 transposon mutants in orthologs

Cross-References

RefSeq NP_252287.1
GI 15598793
Affymetrix PA3597_at
Entrez 880202
GenBank AAG06985.1
INSDC AAG06985.1
NCBI Locus Tag PA3597
protein_id(GenBank) gb|AAG06985.1|AE004780_4|gnl|PseudoCAP|PA3597
TIGR NTL03PA03597
UniParc UPI00000C5A84
UniProtKB Acc Q9HY29
UniProtKB ID Q9HY29_PSEAE
UniRef100 UniRef100_Q9HY29
UniRef50 UniRef50_Q4K705
UniRef90 UniRef90_A0A080VXD5

Product

Feature Type CDS
Coding Frame 1
Product Name
probable amino acid permease
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) 3.55
Kyte-Doolittle Hydrophobicity Value 0.846
Molecular Weight (kDa) 47.3
Isoelectric Point (pI) 8.30

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 444 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000219 (3043 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3597

Human Homologs

Ensembl 110, assembly GRCh38.p14
solute carrier family 7 member 7 [Source:HGNC Symbol;Acc:HGNC:11065]
E-value: 8.4e-11
Percent Identity: 24.4
Ensembl 110, assembly GRCh38.p14
solute carrier family 7 member 7 [Source:HGNC Symbol;Acc:HGNC:11065]
E-value: 8.4e-11
Percent Identity: 24.4
Ensembl 110, assembly GRCh38.p14
solute carrier family 7 member 7 [Source:HGNC Symbol;Acc:HGNC:11065]
E-value: 8.4e-11
Percent Identity: 24.4
Ensembl 110, assembly GRCh38.p14
solute carrier family 7 member 7 [Source:HGNC Symbol;Acc:HGNC:11065]
E-value: 8.4e-11
Percent Identity: 24.4
Ensembl 110, assembly GRCh38.p14
solute carrier family 7 member 7 [Source:HGNC Symbol;Acc:HGNC:11065]
E-value: 8.4e-11
Percent Identity: 24.4
Ensembl 110, assembly GRCh38.p14
solute carrier family 7 member 7 [Source:HGNC Symbol;Acc:HGNC:11065]
E-value: 8.4e-11
Percent Identity: 24.4
Ensembl 110, assembly GRCh38.p14
solute carrier family 7 member 7 [Source:HGNC Symbol;Acc:HGNC:11065]
E-value: 8.4e-11
Percent Identity: 24.4

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295