Pseudomonas aeruginosa PAO1, PA3603 (dgkA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3603
Name
dgkA
Replicon chromosome
Genomic location 4037945 - 4038316 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_252293.1
GI 15598799
Affymetrix PA3603_dgkA_at
DNASU PaCD00007577
Entrez 880149
GenBank AAG06991.1
INSDC AAG06991.1
NCBI Locus Tag PA3603
protein_id(GenBank) gb|AAG06991.1|AE004780_10|gnl|PseudoCAP|PA3603
TIGR NTL03PA03603
UniParc UPI00000C5A88
UniProtKB Acc Q9HY23
UniProtKB ID KDGL_PSEAE
UniRef100 UniRef100_Q9HY23
UniRef50 UniRef50_Q9HY23
UniRef90 UniRef90_Q9HY23

Product

Feature Type CDS
Coding Frame 1
Product Name
diacylglycerol kinase
Product Name Confidence: Class 2
Synonyms diglyceride kinase
Evidence for Translation
Charge (pH 7) 3.19
Kyte-Doolittle Hydrophobicity Value 0.762
Molecular Weight (kDa) 13.1
Isoelectric Point (pI) 10.03

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 225 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002071 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3603
Search term: dgkA

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Membrane topology of Escherichia coli diacylglycerol kinase.
Smith RL, O'Toole JF, Maguire ME, Sanders CR 2nd
J Bacteriol 1994 Sep;176(17):5459-65
PubMed ID: 8071224