Pseudomonas aeruginosa PAO1, PA3608 (potB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3608
Name
potB
Replicon chromosome
Genomic location 4042175 - 4043068 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252298.1
GI 15598804
Affymetrix PA3608_potB_at
Entrez 880430
GenBank AAG06996.1
INSDC AAG06996.1
NCBI Locus Tag PA3608
protein_id(GenBank) gb|AAG06996.1|AE004781_4|gnl|PseudoCAP|PA3608
TIGR NTL03PA03608
UniParc UPI00000C5A8D
UniProtKB Acc Q9HY18
UniProtKB ID Q9HY18_PSEAE
UniRef100 UniRef100_Q9HY18
UniRef50 UniRef50_Q9HY18
UniRef90 UniRef90_Q9HY18

Product

Feature Type CDS
Coding Frame 1
Product Name
polyamine transport protein PotB
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 5.61
Kyte-Doolittle Hydrophobicity Value 0.729
Molecular Weight (kDa) 32.7
Isoelectric Point (pI) 9.27

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 499 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002066 (298 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3608
Search term: potB

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Characteristics of the gene for a spermidine and putrescine transport system that maps at 15 min on the Escherichia coli chromosome.
Furuchi T, Kashiwagi K, Kobayashi H, Igarashi K
J Biol Chem 1991 Nov 5;266(31):20928-33
PubMed ID: 1939142
Characteristics of the operon for a putrescine transport system that maps at 19 minutes on the Escherichia coli chromosome.
Pistocchi R, Kashiwagi K, Miyamoto S, Nukui E, Sadakata Y, Kobayashi H, Igarashi K
J Biol Chem 1993 Jan 5;268(1):146-52
PubMed ID: 8416922