Pseudomonas aeruginosa PAO1, PA3625 (surE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3625
Name
surE
Replicon chromosome
Genomic location 4060625 - 4061374 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252315.1
GI 15598821
Affymetrix PA3625_surE_at
DNASU PaCD00007587
Entrez 880442
GenBank AAG07013.1
INSDC AAG07013.1
NCBI Locus Tag PA3625
protein_id(GenBank) gb|AAG07013.1|AE004782_11|gnl|PseudoCAP|PA3625
TIGR NTL03PA03625
UniParc UPI000013625F
UniProtKB Acc Q9HY05
UniProtKB ID SURE_PSEAE
UniRef100 UniRef100_Q02R97
UniRef50 UniRef50_Q83JY2
UniRef90 UniRef90_Q02R97

Product

Feature Type CDS
Coding Frame 1
Product Name
survival protein SurE
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.14
Kyte-Doolittle Hydrophobicity Value 0.073
Molecular Weight (kDa) 26.4
Isoelectric Point (pI) 5.24

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 499 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002049 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3625
Search term: surE

Human Homologs

References

A new gene involved in stationary-phase survival located at 59 minutes on the Escherichia coli chromosome.
Li C, Ichikawa JK, Ravetto JJ, Kuo HC, Fu JC, Clarke S
J Bacteriol 1994 Oct;176(19):6015-22
PubMed ID: 7928962
Mutations in the Escherichia coli surE gene increase isoaspartyl accumulation in a strain lacking the pcm repair methyltransferase but suppress stress-survival phenotypes.
Visick JE, Ichikawa JK, Clarke S
FEMS Microbiol Lett 1998 Oct 1;167(1):19-25
PubMed ID: 9785447