Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3645
|
Name |
fabZ
Synonym: sefA |
Replicon | chromosome |
Genomic location | 4082958 - 4083398 (- strand) |
RefSeq | NP_252335.1 |
GI | 15598841 |
Affymetrix | PA3645_fabZ_at |
DNASU | PaCD00007598 |
Entrez | 880494 |
GenBank | AAG07033.1 |
INSDC | AAG07033.1 |
NCBI Locus Tag | PA3645 |
protein_id(GenBank) | gb|AAG07033.1|AE004784_6|gnl|PseudoCAP|PA3645 |
TIGR | NTL03PA03645 |
UniParc | UPI000012A4B1 |
UniProtKB Acc | Q9HXY7 |
UniProtKB ID | FABZ_PSEAE |
UniRef100 | UniRef100_A6V1E3 |
UniRef50 | UniRef50_Q1H150 |
UniRef90 | UniRef90_A6V1E3 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | 1.10 |
Kyte-Doolittle Hydrophobicity Value | -0.053 |
Molecular Weight (kDa) | 16.8 |
Isoelectric Point (pI) | 7.56 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
1U1Z | LYASE | 07/16/04 | The Structure of (3R)-hydroxyacyl-ACP dehydratase (FabZ) | Pseudomonas aeruginosa | 2.5 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 505 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002029 (537 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3645
Search term: fabZ
|
An Escherichia coli gene (FabZ) encoding (3R)-hydroxymyristoyl acyl carrier protein dehydrase. Relation to fabA and suppression of mutations in lipid A biosynthesis.
Mohan S, Kelly TM, Eveland SS, Raetz CR, Anderson MS
J Biol Chem 1994 Dec 30;269(52):32896-903
PubMed ID: 7806516
|
Structure of a dehydratase-isomerase from the bacterial pathway for biosynthesis of unsaturated fatty acids: two catalytic activities in one active site.
Leesong M, Henderson BS, Gillig JR, Schwab JM, Smith JL
Structure 1996 Mar 15;4(3):253-64
PubMed ID: 8805534
|