Pseudomonas aeruginosa PAO1, PA3699

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3699
Name
Replicon chromosome
Genomic location 4139959 - 4140672 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252389.1
GI 15598895
Affymetrix PA3699_at
Entrez 879135
GenBank AAG07087.1
INSDC AAG07087.1
NCBI Locus Tag PA3699
protein_id(GenBank) gb|AAG07087.1|AE004789_7|gnl|PseudoCAP|PA3699
TIGR NTL03PA03699
UniParc UPI00000C5AC7
UniProtKB Acc Q9HXU1
UniProtKB ID Q9HXU1_PSEAE
UniRef100 UniRef100_W0YY78
UniRef50 UniRef50_W6QRX7
UniRef90 UniRef90_A6V188

Product

Feature Type CDS
Coding Frame 1
Product Name
probable transcriptional regulator
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.03
Kyte-Doolittle Hydrophobicity Value -0.078
Molecular Weight (kDa) 26.3
Isoelectric Point (pI) 5.40

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3KKD transcription regulator 11/05/09 Structure of a putative tetr transcriptional regulator (pa3699) from pseudomonas aeruginosa pa01 Pseudomonas aeruginosa PAO1 2.1 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 60 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001978 (500 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3699

Human Homologs

References

A new transcriptional repressor of the pseudomonas aeruginosa quorum sensing receptor gene lasR.
Longo F, Rampioni G, Bondì R, Imperi F, Fimia GM, Visca P, Zennaro E, Leoni L
PLoS One 2013;8(7):e69554
PubMed ID: 23861975