Pseudomonas aeruginosa PAO1, PA3704 (wspE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3704
Name
wspE
Replicon chromosome
Genomic location 4145943 - 4148252 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252393.1
GI 15598899
Affymetrix PA3704_at
Entrez 880394
GenBank AAG07091.1
INSDC AAG07091.1
NCBI Locus Tag PA3704
protein_id(GenBank) gb|AAG07091.1|AE004789_11|gnl|PseudoCAP|PA3704
TIGR NTL03PA03704
UniParc UPI00000C5ACB
UniProtKB Acc Q9HXT7
UniProtKB ID Q9HXT7_PSEAE
UniRef100 UniRef100_U8NKA0
UniRef50 UniRef50_K9NDV8
UniRef90 UniRef90_Q02RH6

Product

Feature Type CDS
Coding Frame 1
Product Name
probable chemotaxis sensor/effector fusion protein
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -29.21
Kyte-Doolittle Hydrophobicity Value -0.165
Molecular Weight (kDa) 84.3
Isoelectric Point (pI) 4.81

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 619 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001975 (449 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3704
Search term: wspE

Human Homologs

References

Autolysis and autoaggregation in Pseudomonas aeruginosa colony morphology mutants.
D'Argenio DA, Calfee MW, Rainey PB, Pesci EC
J Bacteriol 2002 Dec;184(23):6481-9
PubMed ID: 12426335
Purification and characterization of the Myxococcus xanthus FrzE protein shows that it has autophosphorylation activity.
McCleary WR, Zusman DR
J Bacteriol 1990 Dec;172(12):6661-8
PubMed ID: 2123853